List of voice actors in the cartoon show
- Charlie Adler - Nat Smurfling
- Jack Angel
- Michael Bell - Grouchy Smurf, Handy Smurf, Lazy Smurf, Sir Johan
- Lucille Bliss - Smurfette
- Susan Blu - Nanny Smurf, Pansy
- Ruth Buzzi
- Bill Callaway - Clumsy Smurf, Painter Smurf
- Hamilton Camp - Greedy Smurf, Harmony Smurf
- Brian Cummings
- Jim Cummings - Sultan of Sweets
- Keene Curtis - Lord Balthazar
- Jennifer Darling - Princess Savina
- Marshall Efron - Sloppy Smurf
- Bernard Erhard - Timber Smurf
- June Foray - Jokey Smurf, Mother Nature
- Pat Fraley - Tuffy Smurf
- Ed Gilbert
- Danny Goldman - Brainy Smurf
- Bob Holt - The King
- Kip King - Tailor Smurf
- Tress MacNeille
- Kenneth Mars
- Amanda McBroom - Chlorhydris
- Julie McWhirter - Baby Smurf, Sassette Smurfling
- Don Messick - Papa Smurf, Azrael, Dreamy Smurf, Sweepy Smurf
- Pierce Mullen - Dame Barbara
- Pat Musick - Snappy Smurfling
- Noelle North - Slouchy Smurfling
- Alan Oppenheimer - Vanity Smurf, Enchanter Homnibus, Father Time
- Rob Paulsen - Marco Smurf
- Henry Polic II - Tracker Smurf
- Philip Proctor - King Gerard
- Dan Radloff
- Hal Smith
- Kath Soucie - Ali Babies
- John Stephenson
- Russi Taylor - Smoogle
- Brenda Vaccaro - Scruple
- Janet Waldo - Hogatha
- Lennie Weinrib - Bigmouth
- Frank Welker - Clockwork Smurf, Hefty Smurf, Peewit, Poet Smurf, Puppy, Wild Smurf, Nemesis
- Paul Winchell - Gargamel, Nosey Smurf
- Jonathan Winters - Grandpa Smurf
- Alan Young - Miner Smurf, Farmer Smurf, Scaredy Smurf
List of voice actors in The Smurfs film series
- Jonathan Winters - Papa Smurf (The Smurfs and The Smurfs 2)
- Jack Angel - Papa Smurf (The Smurfs: A Christmas Carol)
- Katy Perry - Smurfette (The Smurfs and The Smurfs 2)
- Melissa Sturm - Smurfette (The Smurfs: A Christmas Carol)
- Fred Armisen - Brainy Smurf
- Anton Yelchin - Clumsy Smurf
- George Lopez - Grouchy Smurf
- Alan Cumming - Gutsy Smurf
- Gary Basaraba - Hefty Smurf
- Jeff Foxworthy - Handy Smurf
- Paul Reubens - Jokey Smurf
- John Oliver - Vanity Smurf
- Wolfgang Puck - Chef Smurf
- B.J. Novak - Baker Smurf
- Kenan Thompson - Greedy Smurf
- Tom Kane - Narrator Smurf
- John Kassir - Crazy Smurf
- Christina Ricci - Vexy
- J.B. Smoove - Hackus
- Frank Welker - Azrael