Papa Smurf's laboratory is the center location of Papa Smurf's activities in the Smurfs comic books, the 1980s Smurfs cartoon show, the 2011 Smurfs movie, and the 2021 TV series. It is where he works on various formulas, either by himself or with Brainy as his assistant. Usually his laboratory is separate from his own personal house, and is off-limits to every Smurf.